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10.1242/dev.128074 http://scihub22266oqcxt.onion/10.1242/dev.128074 C4920157!4920157 !27246710     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27246710 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Development 2016 ; 143 (11 ): 1838-47 Nephropedia Template TP {{tp|p=27246710 |t=2016. Circular RNAs: analysis, expression and potential functions |pdf=|usr=}}{{27246710 }} gab.com Text Circular RNAs: analysis, expression and potential functions JO: Development http://www.kidney.de/pget.php?&tw=1&pmid=27246710 #FOAvip Just a few years ago, it had been assumed that the dominant RNA isoforms produced from eukaryotic genes were variants of messenger RNA, functioning as intermediates in gene expression. In early 2012, however, a surprising discovery was made: circular RNA (circRNA) was shown to be a transcriptional product in thousands of human and mouse genes and in hundreds of cases constituted the dominant RNA isoform. Subsequent studies revealed that the expression of circRNAs is developmentally regulated, tissue and cell-type specific, and shared across the eukaryotic tree of life. These features suggest important functions for these molecules. Here, we describe major advances in the field of circRNA biology, focusing on the regulation of and functional roles played by these molecules. Twit Text FOAVip Circular RNAs: analysis, expression and potential functions ????Development http://www.kidney.de/pget.php?&tw=1&pmid=27246710 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27246710 #FOAvip English Wikipedia <ref>{{Cite pmid|27246710 }}</ref> Circular RNAs: analysis, expression and potential functions #MMPMID27246710 Barrett SP ; Salzman J Development 2016[Jun]; 143 (11 ): 1838-47 PMID27246710 show ga Just a few years ago, it had been assumed that the dominant RNA isoforms produced from eukaryotic genes were variants of messenger RNA, functioning as intermediates in gene expression. In early 2012, however, a surprising discovery was made: circular RNA (circRNA) was shown to be a transcriptional product in thousands of human and mouse genes and in hundreds of cases constituted the dominant RNA isoform. Subsequent studies revealed that the expression of circRNAs is developmentally regulated, tissue and cell-type specific, and shared across the eukaryotic tree of life. These features suggest important functions for these molecules. Here, we describe major advances in the field of circRNA biology, focusing on the regulation of and functional roles played by these molecules. |*Gene Expression Regulation [MESH] |Animals [MESH] |Computational Biology [MESH] |Humans [MESH] |Models, Genetic [MESH] |RNA Splicing/genetics [MESH] |RNA, Circular [MESH]Circular RNAs: analysis, expression and potential functions (epmc).pdf DeepDyve Pubget Overpricing