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2016 ; 1
(5
): 128-135
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Chronic osteomyelitis: what the surgeon needs to know
#MMPMID28461939
Panteli M
; Giannoudis PV
EFORT Open Rev
2016[May]; 1
(5
): 128-135
PMID28461939
show ga
Chronic osteomyelitis represents a progressive inflammatory process caused by
pathogens, resulting in bone destruction and sequestrum formation.It may present
with periods of quiescence of variable duration, whereas its occurrence, type,
severity and prognosis is multifactorial.The 'gold standard' for the diagnosis of
chronic osteomyelitis is the presence of positive bone cultures and
histopathologic examination of the bone.Its management remains challenging to the
treating physician, with a multidisciplinary approach involving radiologists,
microbiologists with expertise in infectious diseases, orthopaedic surgeons and
plastic surgeons.Treatment should be tailored to each patient according the
severity and duration of symptoms, as well as to the clinical and radiological
response to treatment.A combined antimicrobial and surgical treatment should be
considered in all cases, including appropriate dead space management and
subsequent reconstruction. Relapse can occur, even following an apparently
successful treatment, which has a major impact on the quality of life of patients
and is a substantial financial burden to any healthcare system. Cite this article
EFORT Open Rev 2016;1:128-135. DOI: 10.1302/2058-5241.1.000017.