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10.1016/j.molcel.2016.05.024 http://scihub22266oqcxt.onion/10.1016/j.molcel.2016.05.024 C4893772!4893772 !27259199     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27259199 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27259199 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Mol+Cell 2016 ; 62 (5 ): 665-7 Nephropedia Template TP {{tp|p=27259199 |t=2016. Chromatin Scanning by Dynamic Binding of Pioneer Factors |pdf=|usr=}}{{27259199 }} gab.com Text Chromatin Scanning by Dynamic Binding of Pioneer Factors JO: Mol Cell http://www.kidney.de/pget.php?&tw=1&pmid=27259199 #FOAvip Pioneer factors such as FoxA target nucleosomal DNA and initiate cooperative interactions at silent genes during development, cellular reprogramming, and steroid hormone induction. Biophysical studies previously showed that the nuclear mobility of FoxA1 is slower than for many other transcription factors, whereas a new single molecule study (Swinstead et al., 2016, Cell) shows comparable chromatin residence times for FoxA1 and steroid receptors. Despite that steroid receptors engage nucleosome-remodeling complexes, the vast majority of co-bound sites with FoxA are dependent upon FoxA, not vice versa. Taken together, the distinguishing feature of pioneer factors remains nucleosomal access rather than an exceptional residence time in chromatin. Twit Text FOAVip Chromatin Scanning by Dynamic Binding of Pioneer Factors ????Mol Cell http://www.kidney.de/pget.php?&tw=1&pmid=27259199 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27259199 #FOAvip English Wikipedia <ref>{{Cite pmid|27259199 }}</ref> Chromatin Scanning by Dynamic Binding of Pioneer Factors #MMPMID27259199 Zaret KS ; Lerner J ; Iwafuchi-Doi M Mol Cell 2016[Jun]; 62 (5 ): 665-7 PMID27259199 show ga Pioneer factors such as FoxA target nucleosomal DNA and initiate cooperative interactions at silent genes during development, cellular reprogramming, and steroid hormone induction. Biophysical studies previously showed that the nuclear mobility of FoxA1 is slower than for many other transcription factors, whereas a new single molecule study (Swinstead et al., 2016, Cell) shows comparable chromatin residence times for FoxA1 and steroid receptors. Despite that steroid receptors engage nucleosome-remodeling complexes, the vast majority of co-bound sites with FoxA are dependent upon FoxA, not vice versa. Taken together, the distinguishing feature of pioneer factors remains nucleosomal access rather than an exceptional residence time in chromatin. |Animals [MESH] |Binding Sites [MESH] |Cell Nucleus/*metabolism/ultrastructure [MESH] |Cellular Reprogramming [MESH] |Chromatin Assembly and Disassembly [MESH] |DNA/genetics/*metabolism [MESH] |Gene Expression Regulation, Developmental [MESH] |Gonadal Steroid Hormones/biosynthesis/genetics [MESH] |Hepatocyte Nuclear Factor 3-alpha/genetics/*metabolism [MESH] |Humans [MESH] |Nucleosomes/genetics/*metabolism [MESH] |Protein Binding [MESH]Chromatin Scanning by Dynamic Binding of Pioneer Factors (epmc).pdf DeepDyve Pubget Overpricing