Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27019695
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 F1000Res
2016 ; 5
(ä): 274
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Chromas from chromatin: sonification of the epigenome
#MMPMID27019695
Cittaro D
; Lazarevic D
; Provero P
F1000Res
2016[]; 5
(ä): 274
PMID27019695
show ga
The epigenetic modifications are organized in patterns determining the functional
properties of the underlying genome. Such patterns, typically measured by
ChIP-seq assays of histone modifications, can be combined and translated into
musical scores, summarizing multiple signals into a single waveform. As music is
recognized as a universal way to convey meaningful information, we wanted to
investigate properties of music obtained by sonification of ChIP-seq data. We
show that the music produced by such quantitative signals is perceived by human
listeners as more pleasant than that produced from randomized signals. Moreover,
the waveform can be analyzed to predict phenotypic properties, such as
differential gene expression.