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10.1038/nrmicro.2016.30

http://scihub22266oqcxt.onion/10.1038/nrmicro.2016.30
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C4886739!4886739 !27108705
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suck abstract from ncbi


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pmid27108705
      Nat+Rev+Microbiol 2016 ; 14 (6 ): 385-400
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  • Chlamydia cell biology and pathogenesis #MMPMID27108705
  • Elwell C ; Mirrashidi K ; Engel J
  • Nat Rev Microbiol 2016[Jun]; 14 (6 ): 385-400 PMID27108705 show ga
  • Chlamydia spp. are important causes of human disease for which no effective vaccine exists. These obligate intracellular pathogens replicate in a specialized membrane compartment and use a large arsenal of secreted effectors to survive in the hostile intracellular environment of the host. In this Review, we summarize the progress in decoding the interactions between Chlamydia spp. and their hosts that has been made possible by recent technological advances in chlamydial proteomics and genetics. The field is now poised to decipher the molecular mechanisms that underlie the intimate interactions between Chlamydia spp. and their hosts, which will open up many exciting avenues of research for these medically important pathogens.
  • |*Host-Pathogen Interactions/genetics [MESH]
  • |Bacterial Proteins/metabolism [MESH]
  • |Chlamydia Infections/immunology/*microbiology/physiopathology [MESH]
  • |Chlamydia trachomatis/*pathogenicity/physiology [MESH]
  • |Chlamydia/genetics/immunology/*pathogenicity/physiology [MESH]
  • |Cytoplasm/metabolism/*microbiology [MESH]
  • |Humans [MESH]
  • |Immunity, Innate [MESH]
  • |Proteomics [MESH]


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