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10.1021/ml400498d

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C4060934!4060934 !24944736
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suck abstract from ncbi


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pmid24944736
      ACS+Med+Chem+Lett 2014 ; 5 (6 ): 644-6
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  • Chemogenesis of an antiangiogenic glycosaminoglycan #MMPMID24944736
  • Raman K ; Arungundram S ; Kuberan B
  • ACS Med Chem Lett 2014[Jun]; 5 (6 ): 644-6 PMID24944736 show ga
  • In this letter we report a facile chemical conversion of heparin, a potent anticoagulant with minimal antiangiogenic activity, into an effective antiangiogenic glycosaminoglycan through optimized chemical approaches. This work highlights the potential for industrial scale production of a therapeutic anticancer glycosaminoglycan.
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