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10.1179/2049396714Y.0000000102

http://scihub22266oqcxt.onion/10.1179/2049396714Y.0000000102
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suck abstract from ncbi


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pmid25631575
      Int+J+Occup+Environ+Health 2015 ; 21 (3 ): 241-50
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  • Changes in kidney function among Nicaraguan sugarcane workers #MMPMID25631575
  • Laws RL ; Brooks DR ; Amador JJ ; Weiner DE ; Kaufman JS ; Ramírez-Rubio O ; Riefkohl A ; Scammell MK ; López-Pilarte D ; Sánchez JM ; Parikh CR ; McClean MD
  • Int J Occup Environ Health 2015[Jul]; 21 (3 ): 241-50 PMID25631575 show ga
  • BACKGROUND: There is an epidemic of chronic kidney disease (CKD) of unknown etiology in Central American workers. OBJECTIVES: To investigate changes and job-specific differences in kidney function over a 6-month sugarcane harvest season, explore the potential role of hydration, and measure proteinuria. METHODS: We recruited 284 Nicaraguan sugarcane workers performing seven distinct tasks. We measured urine albumin and serum creatinine and estimated glomerular filtration rate (eGFR). RESULTS: eGFR varied by job and decreased during the harvest in seed cutters (-8·6 ml/min/1·73 m(2)), irrigators (-7·4 ml/min/1·73 m(2)), and cane cutters (-5·0 ml/min/1·73 m(2)), as compared to factory workers. The number of years employed at the company was negatively associated with eGFR. Fewer than 5% of workers had albumin-to-creatinine ratio (ACR) >30 mg/g. CONCLUSIONS: The decline in kidney function during the harvest and the differences by job category and employment duration provide evidence that one or more risk factors of CKD are occupational.
  • |*Farmers [MESH]
  • |*Saccharum [MESH]
  • |Adolescent [MESH]
  • |Adult [MESH]
  • |Albuminuria [MESH]
  • |Creatinine/blood [MESH]
  • |Female [MESH]
  • |Glomerular Filtration Rate [MESH]
  • |Humans [MESH]
  • |Kidney Diseases/blood/*epidemiology/physiopathology/urine [MESH]
  • |Male [MESH]
  • |Middle Aged [MESH]
  • |Nicaragua/epidemiology [MESH]
  • |Occupational Diseases/blood/*epidemiology/physiopathology/urine [MESH]
  • |Proteinuria/blood/*epidemiology/physiopathology/urine [MESH]


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