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2016 ; 70
(3
): 203-7
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Challenges In Early Glaucoma Detection
#MMPMID27594747
Dervisevic E
; Pavljasevic S
; Dervisevic A
; Kasumovic SS
Med Arch
2016[Jun]; 70
(3
): 203-7
PMID27594747
show ga
INTRODUCTION: Glaucoma is the most common optic neuropathy which is characterized
by progressive loss of retinal ganglion cells, the excavation of the optic nerve
head, associated with defects in the visual field. It is not a disease, but the
final result of united and yet completely unidentified cellular and subcellular
processes and effects of many factors responsible for changes in retinal ganglion
cells leading to their accelerated apoptosis. METHODS: This is a
prospective-retrospective, comparative, randomized clinical trial that included
150 patients, 97 were female and 53 male. The age of patients ranged from 18 to
80 years. RESULTS: The highest degree of myopia in category of tilted optic discs
had patients with large disc (4.05 + -0.65). Values of the degree of myopia have
linearly declined in relation to the size of the oblique disc. The analysis of
the results revealed that the subjects who had a higher degree of myopia
associated with glaucoma had frequent parapapillar atrophy of alpha and beta
zones. The highest percentage of subjects with parapapillar changes were in the
group of patients who had other than glaucoma and myopia (62%), then in the group
of patients with glaucoma only (56%). CONCLUSION: Previous studies on the
relationship between myopia and open-angle glaucoma are based on the results of
observational studies. However, according to recent findings, based on the
available studies, the systematic approach to estimate the association between
myopia and glaucoma does not exist. Disc Damage Likelihood Scale (DDLS) is a new
system for assessing glaucomatous damage of the optic disc which strongly
correlates with the degree of visual field loss.