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10.1016/j.ydbio.2016.02.027

http://scihub22266oqcxt.onion/10.1016/j.ydbio.2016.02.027
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suck abstract from ncbi


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pmid26963675
      Dev+Biol 2016 ; 413 (1 ): 8-15
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  • Centroacinar cells: At the center of pancreas regeneration #MMPMID26963675
  • Beer RL ; Parsons MJ ; Rovira M
  • Dev Biol 2016[May]; 413 (1 ): 8-15 PMID26963675 show ga
  • The process of regeneration serves to heal injury by replacing missing cells. Understanding regeneration can help us replace cell populations lost during disease, such as the insulin-producing ? cells lost in diabetic patients. Centroacinar cells (CACs) are a specialized ductal pancreatic cell type that act as progenitors to replace ? cells in the zebrafish. However, whether CACs contribute to ?-cell regeneration in adult mammals remains controversial. Here we review the current understanding of the role of CACs as endocrine progenitors during regeneration in zebrafish and mammals.
  • |*Regeneration [MESH]
  • |Animals [MESH]
  • |Cell Differentiation [MESH]
  • |Cell Lineage [MESH]
  • |Cell Proliferation [MESH]
  • |Endocrine Cells/cytology [MESH]
  • |Homeostasis [MESH]
  • |Humans [MESH]
  • |Insulin-Secreting Cells/cytology/metabolism [MESH]
  • |Mammals [MESH]
  • |Mice [MESH]
  • |Pancreas/cytology/*embryology/*physiology [MESH]
  • |Pancreatic Ducts/*cytology [MESH]
  • |Signal Transduction [MESH]
  • |Stem Cells/cytology [MESH]


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