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2014 ; 159
(2
): 242-51
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Cellular differences in protein synthesis regulate tissue homeostasis
#MMPMID25303523
Buszczak M
; Signer RA
; Morrison SJ
Cell
2014[Oct]; 159
(2
): 242-51
PMID25303523
show ga
Although sometimes considered a "house-keeping" function, multiple aspects of
protein synthesis are regulated differently among somatic cells, including stem
cells, and can be modulated in a cell-type-specific manner. These differences are
required to establish and maintain differences in cell identity, cell function,
tissue homeostasis, and tumor suppression.