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2015 ; 56
(6
): 412-21
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Cell-based therapy for kidney disease
#MMPMID26078837
Chung HC
; Ko IK
; Atala A
; Yoo JJ
Korean J Urol
2015[Jun]; 56
(6
): 412-21
PMID26078837
show ga
The prevalence of renal disease continues to increase worldwide. When normal
kidney is injured, the damaged renal tissue undergoes pathological and
physiological events that lead to acute and chronic kidney diseases, which
frequently progress to end stage renal failure. Current treatment of these renal
pathologies includes dialysis, which is incapable of restoring full renal
function. To address this issue, cell-based therapy has become a potential
therapeutic option to treat renal pathologies. Recent development in cell therapy
has demonstrated promising therapeutic outcomes, in terms of restoration of renal
structure and function impaired by renal disease. This review focuses on the cell
therapy approaches for the treatment of kidney diseases, including various cell
sources used, as well recent advances made in preclinical and clinical studies.
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