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10.15252/embj.201695383 http://scihub22266oqcxt.onion/10.15252/embj.201695383 C5331751!5331751 !28137748     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28137748 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       EMBO+J 2017 ; 36 (5 ): 568-582 Nephropedia Template TP {{tp|p=28137748 |t=2017. Cell signaling as a cognitive process |pdf=|usr=}}{{28137748 }} gab.com Text Cell signaling as a cognitive process JO: EMBO J http://www.kidney.de/pget.php?&tw=1&pmid=28137748 #FOAvip Cellular identity as defined through morphology and function emerges from intracellular signaling networks that communicate between cells. Based on recursive interactions within and among these intracellular networks, dynamical solutions in terms of biochemical behavior are generated that can differ from those in isolated cells. In this way, cellular heterogeneity in tissues can be established, implying that cell identity is not intrinsically predetermined by the genetic code but is rather dynamically maintained in a cognitive manner. We address how to experimentally measure the flow of information in intracellular biochemical networks and demonstrate that even simple causality motifs can give rise to rich, context-dependent dynamic behavior. The concept how intercellular communication can result in novel dynamical solutions is applied to provide a contextual perspective on cell differentiation and tumorigenesis. Twit Text FOAVip Cell signaling as a cognitive process ????EMBO J http://www.kidney.de/pget.php?&tw=1&pmid=28137748 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28137748 #FOAvip English Wikipedia <ref>{{Cite pmid|28137748 }}</ref> Cell signaling as a cognitive process #MMPMID28137748 Koseska A ; Bastiaens PI EMBO J 2017[Mar]; 36 (5 ): 568-582 PMID28137748 show ga Cellular identity as defined through morphology and function emerges from intracellular signaling networks that communicate between cells. Based on recursive interactions within and among these intracellular networks, dynamical solutions in terms of biochemical behavior are generated that can differ from those in isolated cells. In this way, cellular heterogeneity in tissues can be established, implying that cell identity is not intrinsically predetermined by the genetic code but is rather dynamically maintained in a cognitive manner. We address how to experimentally measure the flow of information in intracellular biochemical networks and demonstrate that even simple causality motifs can give rise to rich, context-dependent dynamic behavior. The concept how intercellular communication can result in novel dynamical solutions is applied to provide a contextual perspective on cell differentiation and tumorigenesis. |*Cell Communication [MESH] |*Cell Differentiation [MESH] |*Gene Expression Regulation [MESH] |*Gene Regulatory Networks [MESH] |*Signal Transduction [MESH] |Animals [MESH]Cell signaling as a cognitive process (epmc).pdf DeepDyve Pubget Overpricing