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2015 ; 16
(10
): 23905-28
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Cardiovascular Complications of Pregnancy
#MMPMID26473833
Gongora MC
; Wenger NK
Int J Mol Sci
2015[Oct]; 16
(10
): 23905-28
PMID26473833
show ga
Pregnancy causes significant metabolic and hemodynamic changes in a woman's
physiology to allow for fetal growth. The inability to adapt to these changes
might result in the development of hypertensive disorders of pregnancy
(hypertension, preeclampsia or eclampsia), gestational diabetes and preterm
birth. Contrary to previous beliefs these complications are not limited to the
pregnancy period and may leave permanent vascular and metabolic damage. There is
in addition, a direct association between these disorders and increased risk of
future cardiovascular disease (CVD, including hypertension, ischemic heart
disease, heart failure and stroke) and diabetes mellitus. Despite abundant
evidence of this association, women who present with these complications of
pregnancy do not receive adequate postpartum follow up and counseling regarding
their increased risk of future CVD. The postpartum period in these women
represents a unique opportunity to intervene with lifestyle modifications
designed to reduce the development of premature cardiovascular complications. In
some cases it allows early diagnosis and treatment of chronic hypertension or
diabetes mellitus. The awareness of this relationship is growing in the medical
community, especially among obstetricians and primary care physicians, who play a
pivotal role in detecting these complications and assuring appropriate follow up.
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