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10.4172/2161-1025.1000114 http://scihub22266oqcxt.onion/10.4172/2161-1025.1000114 C4792115!4792115 !26989575     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26989575 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Transl+Med+(Sunnyvale) 2013 ; 3 (1 ): ä Nephropedia Template TP {{tp|p=26989575 |t=2013. Cardioprotective Role of Caveolae in Ischemia-Reperfusion Injury |pdf=|usr=}}{{26989575 }} gab.com Text Cardioprotective Role of Caveolae in Ischemia-Reperfusion Injury JO: Transl Med (Sunnyvale) http://www.kidney.de/pget.php?&tw=1&pmid=26989575 #FOAvip Caveolae are flask-like invaginations of the plasma membrane enriched in cholesterol, sphingolipids, the marker protein caveolin and the coat protein cavin. In cardiomyocytes, multiple signaling molecules are concentrated and organized within the caveolae to mediate signaling transduction. Recent studies suggest that caveolae and caveolae-associated signaling molecules play an important role in protecting the myocardium against ischemia-reperfusion injury. For example, cardiac-specific overexpression of caveolin-3 has been shown to lead to protection that mimics ischemic preconditioning, while the knockout of caveolin-3 abolished ischemic preconditioning. In this review, we discuss the molecular mechanisms and signaling pathways that are involved in caveolae-mediated cardioprotection, and examine the potential for caveolae as a therapeutic target for pharmaceutical intervention to treat cardiovascular disease. Twit Text FOAVip Cardioprotective Role of Caveolae in Ischemia-Reperfusion Injury ????Transl Med (Sunnyvale) http://www.kidney.de/pget.php?&tw=1&pmid=26989575 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26989575 #FOAvip English Wikipedia <ref>{{Cite pmid|26989575 }}</ref> Cardioprotective Role of Caveolae in Ischemia-Reperfusion Injury #MMPMID26989575 Sun J ; Nguyen T ; Kohr MJ ; Murphy E Transl Med (Sunnyvale) 2013[Oct]; 3 (1 ): ä PMID26989575 show ga Caveolae are flask-like invaginations of the plasma membrane enriched in cholesterol, sphingolipids, the marker protein caveolin and the coat protein cavin. In cardiomyocytes, multiple signaling molecules are concentrated and organized within the caveolae to mediate signaling transduction. Recent studies suggest that caveolae and caveolae-associated signaling molecules play an important role in protecting the myocardium against ischemia-reperfusion injury. For example, cardiac-specific overexpression of caveolin-3 has been shown to lead to protection that mimics ischemic preconditioning, while the knockout of caveolin-3 abolished ischemic preconditioning. In this review, we discuss the molecular mechanisms and signaling pathways that are involved in caveolae-mediated cardioprotection, and examine the potential for caveolae as a therapeutic target for pharmaceutical intervention to treat cardiovascular disease. äCardioprotective Role of Caveolae in Ischemia-Reperfusion Injury (epmc).pdf DeepDyve Pubget Overpricing