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2015 ; 3
(3
): ä Nephropedia Template TP
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English Wikipedia
Candida albicans Biofilm Development and Its Genetic Control
#MMPMID26185083
Desai JV
; Mitchell AP
Microbiol Spectr
2015[Jun]; 3
(3
): ä PMID26185083
show ga
The fungus Candida albicans is a major source of device-associated infection
because of its capacity for biofilm formation. It is part of the natural mucosal
flora and thus has access to available niches that can lead to infection. In this
chapter we discuss the major properties of C. albicans biofilms and the insight
that has been gleaned from their genetic determinants. Our specific areas of
focus include biofilm structure and development, cell morphology and biofilm
formation, biofilm-associated gene expression, the cell surface and adherence,
the extracellular matrix, biofilm metabolism, and biofilm drug resistance.
|*Equipment Contamination
[MESH]
|Antifungal Agents/pharmacology
[MESH]
|Biofilms/drug effects/*growth & development
[MESH]