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10.1016/j.cub.2012.08.002

http://scihub22266oqcxt.onion/10.1016/j.cub.2012.08.002
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C4472467!4472467 !23058807
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suck abstract from ncbi

pmid23058807
      Curr+Biol 2012 ; 22 (19 ): R849-51
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  • Cancer biology: a new RING to Wnt signaling #MMPMID23058807
  • Fearon ER ; Spence JR
  • Curr Biol 2012[Oct]; 22 (19 ): R849-51 PMID23058807 show ga
  • The ?-catenin-dependent Wnt signaling pathway has key roles in embryonic development and adult tissues and is defective in various cancers. Recent studies highlight the function of two transmembrane RING finger ubiquitin ligases in modulating Wnt signaling and reveal roles for mutations in the RING finger proteins in cancer.
  • |*Endocytosis [MESH]
  • |*Wnt Signaling Pathway [MESH]
  • |Animals [MESH]
  • |DNA-Binding Proteins/*metabolism [MESH]
  • |Female [MESH]
  • |Humans [MESH]
  • |Male [MESH]
  • |Oncogene Proteins/*metabolism [MESH]
  • |Receptors, Wnt/*metabolism [MESH]
  • |Stem Cells/*enzymology [MESH]
  • |Thrombospondins/*metabolism [MESH]
  • |Tumor Suppressor Proteins/*metabolism [MESH]


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