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2015 ; 348
(6230
): 80-6
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Cancer and the microbiota
#MMPMID25838377
Garrett WS
Science
2015[Apr]; 348
(6230
): 80-6
PMID25838377
show ga
A host's microbiota may increase, diminish, or have no effect at all on cancer
susceptibility. Assigning causal roles in cancer to specific microbes and
microbiotas, unraveling host-microbiota interactions with environmental factors
in carcinogenesis, and exploiting such knowledge for cancer diagnosis and
treatment are areas of intensive interest. This Review considers how microbes and
the microbiota may amplify or mitigate carcinogenesis, responsiveness to cancer
therapeutics, and cancer-associated complications.