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10.1016/j.ccr.2013.05.016

http://scihub22266oqcxt.onion/10.1016/j.ccr.2013.05.016
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C3706087!3706087 !23763996
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suck abstract from ncbi


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pmid23763996       Cancer+Cell 2013 ; 23 (6 ): 711-3
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  • Cancer Stem Cells Activate STAT3 the EZ Way #MMPMID23763996
  • Fouse SD ; Costello JF
  • Cancer Cell 2013[Jun]; 23 (6 ): 711-3 PMID23763996 show ga
  • Activated STAT3 and increased expression of the histone methyltransferase EZH2 are independently associated with the most malignant subset of gliomas. In this issue of Cancer Cell, Kim and colleagues discover that EZH2 enhances STAT3 activation by trimethylating lysine180 in STAT3 and does so preferentially in glioma stem-like cells.
  • |Animals [MESH]
  • |Enhancer of Zeste Homolog 2 Protein [MESH]
  • |Glioblastoma/*metabolism [MESH]
  • |Humans [MESH]
  • |Polycomb Repressive Complex 2/*physiology [MESH]


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