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10.1016/S2055-6640(20)30489-1 http://scihub22266oqcxt.onion/10.1016/S2055-6640(20)30489-1 C4586130!4586130 !26430703     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26430703 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Virus+Erad 2015 ; 1 (2 ): 67-71 Nephropedia Template TP {{tp|p=26430703 |t=2015. CNS reservoirs for HIV: implications for eradication |pdf=|usr=}}{{26430703 }} gab.com Text CNS reservoirs for HIV: implications for eradication JO: J Virus Erad http://www.kidney.de/pget.php?&tw=1&pmid=26430703 #FOAvip Controversy exists as to whether the central nervous system (CNS) serves as a reservoir site for HIV, in part reflecting the varying perspectives on what constitutes a 'reservoir' versus a mere site of latent viral integration. However, if the CNS proves to be a site of HIV persistence capable of replicating and reseeding the periphery, leading to failure of virological control, this privileged anatomical site would need dedicated consideration during the development of HIV cure strategies. In this review we discuss the current literature focused on the question of the CNS as a reservoir for HIV, covering the clinical evidence for continued CNS involvement despite suppressive therapy, the theorised dynamics of HIV integration into the CNS, as well as studies indicating that HIV can replicate independently and compartmentalise in the CNS. The unique cellular and anatomical sites of HIV integration in the CNS are also reviewed, as are the potential implications for HIV cure strategies. Twit Text FOAVip CNS reservoirs for HIV: implications for eradication ????J Virus Erad http://www.kidney.de/pget.php?&tw=1&pmid=26430703 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26430703 #FOAvip English Wikipedia <ref>{{Cite pmid|26430703 }}</ref> CNS reservoirs for HIV: implications for eradication #MMPMID26430703 Hellmuth J ; Valcour V ; Spudich S J Virus Erad 2015[Apr]; 1 (2 ): 67-71 PMID26430703 show ga Controversy exists as to whether the central nervous system (CNS) serves as a reservoir site for HIV, in part reflecting the varying perspectives on what constitutes a 'reservoir' versus a mere site of latent viral integration. However, if the CNS proves to be a site of HIV persistence capable of replicating and reseeding the periphery, leading to failure of virological control, this privileged anatomical site would need dedicated consideration during the development of HIV cure strategies. In this review we discuss the current literature focused on the question of the CNS as a reservoir for HIV, covering the clinical evidence for continued CNS involvement despite suppressive therapy, the theorised dynamics of HIV integration into the CNS, as well as studies indicating that HIV can replicate independently and compartmentalise in the CNS. The unique cellular and anatomical sites of HIV integration in the CNS are also reviewed, as are the potential implications for HIV cure strategies. äCNS reservoirs for HIV: implications for eradication (epmc).pdf DeepDyve Pubget Overpricing