Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1002/cbic.201402433 http://scihub22266oqcxt.onion/10.1002/cbic.201402433 C4278937!4278937 !25403986     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25403986 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25403986 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Chembiochem 2014 ; 15 (18 ): 2667-73 Nephropedia Template TP {{tp|p=25403986 |t=2014. CHoMP: a chemoenzymatic histology method using clickable probes |pdf=|usr=}}{{25403986 }} gab.com Text CHoMP: a chemoenzymatic histology method using clickable probes JO: Chembiochem http://www.kidney.de/pget.php?&tw=1&pmid=25403986 #FOAvip The characterization of aberrant glycosylation patterns in biopsied patient samples represents a remarkable challenge for scientists and medical doctors due to the lack of specific methods for detection. Here, we report the development of a histological method, dubbed CHoMP-chemoenzymatic histology of membrane polysaccharides-for analyzing glycosylation patterns in mammalian tissues. This method exploits a recombinant glycosyltransferase to transfer a monosaccharide analogue equipped with a chemical handle to a specific cell-surface glycan target, which can then be derivatized with imaging probes by using bioorthogonal click chemistry for visualization. We applied CHoMP to survey changes in expression of N-acetyllactosamine (LacNAc) in human samples from patients afflicted with lung adenocarcinoma and observed a sharp decrease in expression levels between normal and early grade tumors, thus suggesting a potential application of this technique in early cancer diagnosis. Twit Text FOAVip CHoMP: a chemoenzymatic histology method using clickable probes ????Chembiochem http://www.kidney.de/pget.php?&tw=1&pmid=25403986 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25403986 #FOAvip English Wikipedia <ref>{{Cite pmid|25403986 }}</ref> CHoMP: a chemoenzymatic histology method using clickable probes #MMPMID25403986 Rouhanifard SH ; López-Aguilar A ; Wu P Chembiochem 2014[Dec]; 15 (18 ): 2667-73 PMID25403986 show ga The characterization of aberrant glycosylation patterns in biopsied patient samples represents a remarkable challenge for scientists and medical doctors due to the lack of specific methods for detection. Here, we report the development of a histological method, dubbed CHoMP-chemoenzymatic histology of membrane polysaccharides-for analyzing glycosylation patterns in mammalian tissues. This method exploits a recombinant glycosyltransferase to transfer a monosaccharide analogue equipped with a chemical handle to a specific cell-surface glycan target, which can then be derivatized with imaging probes by using bioorthogonal click chemistry for visualization. We applied CHoMP to survey changes in expression of N-acetyllactosamine (LacNAc) in human samples from patients afflicted with lung adenocarcinoma and observed a sharp decrease in expression levels between normal and early grade tumors, thus suggesting a potential application of this technique in early cancer diagnosis. |Adenocarcinoma/*diagnosis/pathology [MESH] |Amino Sugars/*analysis [MESH] |Animals [MESH] |Click Chemistry/methods [MESH] |Glycosylation [MESH] |Histological Techniques/methods [MESH] |Humans [MESH] |Lung Neoplasms/*diagnosis/pathology [MESH] |Lung/*pathology [MESH] |Male [MESH]CHoMP: a chemoenzymatic histology method using clickable probes (epmc).pdf DeepDyve Pubget Overpricing