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2015 ; 88
(4
): 359-65
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Bygiene: The New Paradigm of Bidirectional Hygiene
#MMPMID26604859
Al-Ghalith GA
; Knights D
Yale J Biol Med
2015[Dec]; 88
(4
): 359-65
PMID26604859
show ga
The pervasive dogma surrounding the evolution of virulence - -namely, that a
pathogen's virulence decreases over time to prevent threatening its host -- is an
archaic assertion that is more appropriately cast as an optimization of virulence
cost and benefit. However, the prevailing attitudes underlying practices of
medical hygiene and sanitization remain entrenched in these passé ideas. This is
true despite the emergence of evidence linking those practices to mounting
virulence and antimicrobial resistance in the hospital. It is, therefore, our
position that just as the microbe has sought an optimized balance in virulence,
so should we seek such an optimized balance in vigilance, complementing warfare
with restoration. We call this approach "bygiene," or bidirectional hygiene.