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2013 ; 2013
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Brown-McLean syndrome
#MMPMID24108775
Kam KW
; Jhanji V
; Young AL
BMJ Case Rep
2013[Oct]; 2013
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An 80-year-old Chinese man with high myopia and a history of right eye cataract
extraction and superior peripheral iridectomy developed peripheral corneal oedema
after a period of aphakia. The peripheral corneal oedema was static over years
and did not progress to involve central cornea hence his visual acuity remained
stable. The condition was compatible with the relatively rare Brown-McLean
syndrome. Specular microscopy showed normal endothelial cell density in the
oedematous peripheral as well as central cornea. While anterior segment optical
coherence tomography demonstrated the cross-sectional architecture of cornea,
Scheimpflug imaging was used to measure the peripheral corneal thickening and to
demonstrate increased corneal density as compared with the contralateral normal
eye. These investigations not only help better characterise the rare disease, but
also in precisely monitoring any disease progression by periodic measurements.