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2015 ; 6
(ä): 517
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English Wikipedia
Broad-spectrum antiviral agents
#MMPMID26052325
Zhu JD
; Meng W
; Wang XJ
; Wang HC
Front Microbiol
2015[]; 6
(ä): 517
PMID26052325
show ga
Development of highly effective, broad-spectrum antiviral agents is the major
objective shared by the fields of virology and pharmaceutics. Antiviral drug
development has focused on targeting viral entry and replication, as well as
modulating cellular defense system. High throughput screening of molecules,
genetic engineering of peptides, and functional screening of agents have
identified promising candidates for development of optimal broad-spectrum
antiviral agents to intervene in viral infection and control viral epidemics.
This review discusses current knowledge, prospective applications, opportunities,
and challenges in the development of broad-spectrum antiviral agents.