Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1097/WNR.0000000000000362 http://scihub22266oqcxt.onion/10.1097/WNR.0000000000000362 C4415522!4415522 !25830491     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25830491 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Neuroreport 2015 ; 26 (7 ): 411-5 Nephropedia Template TP {{tp|p=25830491 |t=2015. Brainstem morphological changes in Alzheimer s disease |pdf=|usr=}}{{25830491 }} gab.com Text Brainstem morphological changes in Alzheimer s disease JO: Neuroreport http://www.kidney.de/pget.php?&tw=1&pmid=25830491 #FOAvip As brainstem nuclei are interconnected with several cortical structures and regulate several autonomic, cognitive, and behavioral functions, it might be important to place the brainstem within an important pathologic core in the progression of Alzheimer's disease (AD). Although there have been several postmortem studies reporting neuropathological alterations of the brainstem in AD, there has been no in-vivo structural neuroimaging study of the brainstem in the patients with AD. The aim of this study was to investigate differences in the brainstem volume and shape between patients with AD and elderly normal controls. Fifty AD patients (the Clinical Dementia Rating Scale ? 1) and 50 normal controls were recruited, and the brainstem volumes and deformations were compared between the AD and the controls. Patients with AD showed significant total volume [(mean ± SD) 21007 ± 1640?mm] reduction in the brainstem compared with the controls [(mean ± SD) 22530 ± 1750?mm] (P<0.001). In addition, AD patients showed significant brainstem deformations in the upper posterior brainstem corresponding to the midbrain compared with the healthy individuals (false discovery rate corrected P<0.05). This study is the first to explore brainstem volume change and deformations in AD. These structural changes in the midbrain areas might be at the core of the underlying neurobiological mechanisms of brainstem dysfunction with relevance to their various cognitive and behavioral symptoms such as memory impairment, sleep, and emotional disturbance in AD. However, further longitudinal studies might be needed to confirm these findings. Twit Text FOAVip Brainstem morphological changes in Alzheimer s disease ????Neuroreport http://www.kidney.de/pget.php?&tw=1&pmid=25830491 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25830491 #FOAvip English Wikipedia <ref>{{Cite pmid|25830491 }}</ref> Brainstem morphological changes in Alzheimer s disease #MMPMID25830491 Lee JH ; Ryan J ; Andreescu C ; Aizenstein H ; Lim HK Neuroreport 2015[May]; 26 (7 ): 411-5 PMID25830491 show ga As brainstem nuclei are interconnected with several cortical structures and regulate several autonomic, cognitive, and behavioral functions, it might be important to place the brainstem within an important pathologic core in the progression of Alzheimer's disease (AD). Although there have been several postmortem studies reporting neuropathological alterations of the brainstem in AD, there has been no in-vivo structural neuroimaging study of the brainstem in the patients with AD. The aim of this study was to investigate differences in the brainstem volume and shape between patients with AD and elderly normal controls. Fifty AD patients (the Clinical Dementia Rating Scale ? 1) and 50 normal controls were recruited, and the brainstem volumes and deformations were compared between the AD and the controls. Patients with AD showed significant total volume [(mean ± SD) 21007 ± 1640?mm] reduction in the brainstem compared with the controls [(mean ± SD) 22530 ± 1750?mm] (P<0.001). In addition, AD patients showed significant brainstem deformations in the upper posterior brainstem corresponding to the midbrain compared with the healthy individuals (false discovery rate corrected P<0.05). This study is the first to explore brainstem volume change and deformations in AD. These structural changes in the midbrain areas might be at the core of the underlying neurobiological mechanisms of brainstem dysfunction with relevance to their various cognitive and behavioral symptoms such as memory impairment, sleep, and emotional disturbance in AD. However, further longitudinal studies might be needed to confirm these findings. |Aged [MESH] |Aging/pathology [MESH] |Alzheimer Disease/*pathology [MESH] |Brain Stem/*pathology [MESH] |Female [MESH] |Humans [MESH] |Image Processing, Computer-Assisted [MESH] |Magnetic Resonance Imaging [MESH] |Male [MESH] |Organ Size [MESH]Brainstem morphological changes in Alzheimer s disease (epmc).pdf DeepDyve Pubget Overpricing