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10.1146/annurev-immunol-020711-075041 http://scihub22266oqcxt.onion/10.1146/annurev-immunol-020711-075041 C4401150!4401150 !23516983     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=23516983 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\23516983 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Annu+Rev+Immunol 2013 ; 31 (ä): 345-85 Nephropedia Template TP {{tp|p=23516983 |t=2013. Brain-reactive antibodies and disease |pdf=|usr=}}{{23516983 }} gab.com Text Brain-reactive antibodies and disease JO: Annu Rev Immunol http://www.kidney.de/pget.php?&tw=1&pmid=23516983 #FOAvip Autoimmune diseases currently affect 5-7% of the world's population; in most diseases there are circulating autoantibodies. Brain-reactive antibodies are present in approximately 2-3% of the general population but do not usually contribute to brain pathology. These antibodies penetrate brain tissue only early in development or under pathologic conditions. This restriction on their pathogenicity and the lack of correlation between serum titers and brain pathology have, no doubt, contributed to a delayed appreciation of the contribution of autoantibodies in diseases of the central nervous system. Nonetheless, it is increasingly clear that antibodies can cause damage in the brain and likely initiate or aggravate multiple neurologic conditions; brain-reactive antibodies contribute to symptomatology in autoimmune disease, infectious disease, and malignancy. Twit Text FOAVip Brain-reactive antibodies and disease ????Annu Rev Immunol http://www.kidney.de/pget.php?&tw=1&pmid=23516983 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23516983 #FOAvip English Wikipedia <ref>{{Cite pmid|23516983 }}</ref> Brain-reactive antibodies and disease #MMPMID23516983 Diamond B ; Honig G ; Mader S ; Brimberg L ; Volpe BT Annu Rev Immunol 2013[]; 31 (ä): 345-85 PMID23516983 show ga Autoimmune diseases currently affect 5-7% of the world's population; in most diseases there are circulating autoantibodies. Brain-reactive antibodies are present in approximately 2-3% of the general population but do not usually contribute to brain pathology. These antibodies penetrate brain tissue only early in development or under pathologic conditions. This restriction on their pathogenicity and the lack of correlation between serum titers and brain pathology have, no doubt, contributed to a delayed appreciation of the contribution of autoantibodies in diseases of the central nervous system. Nonetheless, it is increasingly clear that antibodies can cause damage in the brain and likely initiate or aggravate multiple neurologic conditions; brain-reactive antibodies contribute to symptomatology in autoimmune disease, infectious disease, and malignancy. |Animals [MESH] |Antigen-Antibody Reactions/immunology [MESH] |Autoantibodies/*metabolism [MESH] |Brain/*immunology/metabolism/*pathology [MESH] |Cells, Cultured [MESH] |Disease Models, Animal [MESH] |Humans [MESH] |Hypoxia-Ischemia, Brain/*immunology/metabolism/*pathology [MESH]Brain-reactive antibodies and disease (epmc).pdf DeepDyve Pubget Overpricing