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10.1155/2017/2748340

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suck abstract from ncbi


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pmid28630861
      Biomed+Res+Int 2017 ; 2017 (ä): 2748340
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  • Biophysical Mechanisms Mediating Fibrin Fiber Lysis #MMPMID28630861
  • Hudson NE
  • Biomed Res Int 2017[]; 2017 (ä): 2748340 PMID28630861 show ga
  • The formation and dissolution of blood clots is both a biochemical and a biomechanical process. While much of the chemistry has been worked out for both processes, the influence of biophysical properties is less well understood. This review considers the impact of several structural and mechanical parameters on lytic rates of fibrin fibers. The influences of fiber and network architecture, fiber strain, FXIIIa cross-linking, and particle transport phenomena will be assessed. The importance of the mechanical aspects of fibrinolysis is emphasized, and future research avenues are discussed.
  • |*Fibrinolysis [MESH]
  • |Animals [MESH]
  • |Factor XIIIa/*chemistry/metabolism [MESH]
  • |Fibrin/*chemistry/metabolism [MESH]


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