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2017 ; 9
(2
): 79-89
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Biomedical applications of nanotechnology
#MMPMID28510082
Ramos AP
; Cruz MAE
; Tovani CB
; Ciancaglini P
Biophys Rev
2017[Apr]; 9
(2
): 79-89
PMID28510082
show ga
The ability to investigate substances at the molecular level has boosted the
search for materials with outstanding properties for use in medicine. The
application of these novel materials has generated the new research field of
nanobiotechnology, which plays a central role in disease diagnosis, drug design
and delivery, and implants. In this review, we provide an overview of the use of
metallic and metal oxide nanoparticles, carbon-nanotubes, liposomes, and
nanopatterned flat surfaces for specific biomedical applications. The chemical
and physical properties of the surface of these materials allow their use in
diagnosis, biosensing and bioimaging devices, drug delivery systems, and bone
substitute implants. The toxicology of these particles is also discussed in the
light of a new field referred to as nanotoxicology that studies the surface
effects emerging from nanostructured materials.