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2015 ; 137
(1
): 0108021-01080215
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Biomechanics and mechanobiology of trabecular bone: a review
#MMPMID25412137
Oftadeh R
; Perez-Viloria M
; Villa-Camacho JC
; Vaziri A
; Nazarian A
J Biomech Eng
2015[Jan]; 137
(1
): 0108021-01080215
PMID25412137
show ga
Trabecular bone is a highly porous, heterogeneous, and anisotropic material which
can be found at the epiphyses of long bones and in the vertebral bodies. Studying
the mechanical properties of trabecular bone is important, since trabecular bone
is the main load bearing bone in vertebral bodies and also transfers the load
from joints to the compact bone of the cortex of long bones. This review article
highlights the high dependency of the mechanical properties of trabecular bone on
species, age, anatomic site, loading direction, and size of the sample under
consideration. In recent years, high resolution micro finite element methods have
been extensively used to specifically address the mechanical properties of the
trabecular bone and provide unique tools to interpret and model the mechanical
testing experiments. The aims of the current work are to first review the
mechanobiology of trabecular bone and then present classical and new approaches
for modeling and analyzing the trabecular bone microstructure and macrostructure
and corresponding mechanical properties such as elastic properties and strength.
|*Bone and Bones/cytology/injuries/physiology
[MESH]