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10.1016/j.iac.2016.03.004

http://scihub22266oqcxt.onion/10.1016/j.iac.2016.03.004
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C6057475!6057475 !27401625
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suck abstract from ncbi


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pmid27401625
      Immunol+Allergy+Clin+North+Am 2016 ; 36 (3 ): 547-57
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  • Biomarkers in Severe Asthma #MMPMID27401625
  • Wan XC ; Woodruff PG
  • Immunol Allergy Clin North Am 2016[Aug]; 36 (3 ): 547-57 PMID27401625 show ga
  • Biomarkers have been critical for studies of disease pathogenesis and the development of new therapies in severe asthma. In particular, biomarkers of type 2 inflammation have proven valuable for endotyping and targeting new biological agents. Because of these successes in understanding and marking type 2 inflammation, lack of knowledge regarding non-type 2 inflammatory mechanisms in asthma will soon be the major obstacle to the development of new treatments and management strategies in severe asthma. Biomarkers can play a role in these investigations as well by providing insight into the underlying biology in human studies of patients with severe asthma.
  • |*Biomarkers [MESH]
  • |Anti-Asthmatic Agents/administration & dosage/adverse effects/therapeutic use [MESH]
  • |Asthma/*diagnosis/etiology/therapy [MESH]
  • |Clinical Decision-Making [MESH]
  • |Humans [MESH]
  • |Prognosis [MESH]
  • |Severity of Illness Index [MESH]


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