Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27119653
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 G+Ital+Dermatol+Venereol
2016 ; 151
(4
): 365-84
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Biologically distinct subsets of nevi
#MMPMID27119653
Rogers T
; Marino ML
; Raciti P
; Jain M
; Busam KJ
; Marchetti MA
; Marghoob AA
G Ital Dermatol Venereol
2016[Aug]; 151
(4
): 365-84
PMID27119653
show ga
Melanocytic nevi (MN) encompass a range of benign tumors with varying microscopic
and macroscopic features. Their development is a multifactorial process under
genetic and environmental influences. The clinical importance of MN lies in
distinguishing them from melanoma and in recognizing their associations with
melanoma risk and cancer syndromes. Historically, the distinction between the
different types of MN, as well as between MN and melanoma, was based on clinical
history, gross morphology, and histopathological features. While histopathology
with clinical correlation remains the gold standard for differentiating and
diagnosing melanocytic lesions, in some cases, this may not be possible. The use
of dermoscopy has allowed for the assessment of subsurface skin structures and
has contributed to the clinical evaluation and classification of MN. Genetic
profiling, while still in its early stages, has the greatest potential to refine
the classification of MN by clarifying their developmental processes, biological
behaviors, and relationships to melanoma. Here we review the most salient
clinical, dermoscopic, histopathological, and genetic features of different MN
subgroups.
free
free
free
