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2015 ; 25
(10
): 1417-22
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English Wikipedia
Biological data sciences in genome research
#MMPMID26430150
Schatz MC
Genome Res
2015[Oct]; 25
(10
): 1417-22
PMID26430150
show ga
The last 20 years have been a remarkable era for biology and medicine. One of the
most significant achievements has been the sequencing of the first human genomes,
which has laid the foundation for profound insights into human genetics, the
intricacies of regulation and development, and the forces of evolution.
Incredibly, as we look into the future over the next 20 years, we see the very
real potential for sequencing more than 1 billion genomes, bringing even deeper
insight into human genetics as well as the genetics of millions of other species
on the planet. Realizing this great potential for medicine and biology, though,
will only be achieved through the integration and development of highly scalable
computational and quantitative approaches that can keep pace with the rapid
improvements to biotechnology. In this perspective, I aim to chart out these
future technologies, anticipate the major themes of research, and call out the
challenges ahead. One of the largest shifts will be in the training used to
prepare the class of 2035 for their highly interdisciplinary world.
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