Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26620568
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26620568
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Theor+Biol+Med+Model
2015 ; 12
(ä): 29
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Bioengineering thermodynamics of biological cells
#MMPMID26620568
Lucia U
Theor Biol Med Model
2015[Dec]; 12
(ä): 29
PMID26620568
show ga
BACKGROUND: Cells are open complex thermodynamic systems. They can be also
regarded as complex engines that execute a series of chemical reactions. Energy
transformations, thermo-electro-chemical processes and transports phenomena can
occur across the cells membranes. Moreover, cells can also actively modify their
behaviours in relation to changes in their environment. METHODS: Different
thermo-electro-biochemical behaviours occur between health and disease states.
But, all the living systems waste heat, which is no more than the result of their
internal irreversibility. This heat is dissipated into the environment. But, this
wasted heat represent also a sort of information, which outflows from the cell
toward its environment, completely accessible to any observer. RESULTS: The
analysis of irreversibility related to this wasted heat can represent a new
approach to study the behaviour of the cells themselves and to control their
behaviours. So, this approach allows us to consider the living systems as black
boxes and analyze only the inflows and outflows and their changes in relation to
the modification of the environment. Therefore, information on the systems can be
obtained by analyzing the changes in the cell heat wasted in relation to external
perturbations. CONCLUSIONS: The bioengineering thermodynamics bases are
summarized and used to analyse possible controls of the calls behaviours based on
the control of the ions fluxes across the cells membranes.