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10.1136/rmdopen-2014-000011

http://scihub22266oqcxt.onion/10.1136/rmdopen-2014-000011
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C4612697!4612697 !26509047
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suck abstract from ncbi


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pmid26509047
      RMD+Open 2015 ; 1 (1 ): e000011
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  • Belimumab in systemic lupus erythematosus #MMPMID26509047
  • Vilas-Boas A ; Morais SA ; Isenberg DA
  • RMD Open 2015[]; 1 (1 ): e000011 PMID26509047 show ga
  • Systemic lupus erythematosus (SLE) is one of the most challenging autoimmune disorders with a complex pathophysiology and diverse clinical presentation. Many drugs have been used to treat SLE with suboptimal results, especially in patients with moderate-to-severe disease. Belimumab is the first biological drug to be approved for the treatment of SLE in more than 50?years. This monoclonal antibody blocks B-cell activating factor, a cytokine important for B-cell differentiation and survival. In this review we focus on the activity of belimumab in patients with SLE and discuss the controversies of its use.
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