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10.1038/nn.4110 http://scihub22266oqcxt.onion/10.1038/nn.4110 C4583818!4583818 !26368943     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26368943 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26368943 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Nat+Neurosci 2015 ; 18 (10 ): 1501-8 Nephropedia Template TP {{tp|p=26368943 |t=2015. Basal forebrain neuronal inhibition enables rapid behavioral stopping |pdf=|usr=}}{{26368943 }} gab.com Text Basal forebrain neuronal inhibition enables rapid behavioral stopping JO: Nat Neurosci http://www.kidney.de/pget.php?&tw=1&pmid=26368943 #FOAvip Cognitive inhibitory control, the ability to rapidly suppress responses inappropriate for the context, is essential for flexible and adaptive behavior. Although most studies on inhibitory control have focused on the fronto-basal-ganglia circuit, we found that rapid behavioral stopping is enabled by neuronal inhibition in the basal forebrain (BF). In rats performing the stop signal task, putative noncholinergic BF neurons with phasic bursting responses to the go signal were nearly completely inhibited by the stop signal. The onset of BF neuronal inhibition was tightly coupled with and temporally preceded the latency to stop, the stop signal reaction time. Artificial inhibition of BF activity in the absence of the stop signal was sufficient to reproduce rapid behavioral stopping. These results reveal a previously unknown subcortical mechanism of rapid inhibitory control by the BF, which provides bidirectional control over the speed of response generation and inhibition. Twit Text FOAVip Basal forebrain neuronal inhibition enables rapid behavioral stopping ????Nat Neurosci http://www.kidney.de/pget.php?&tw=1&pmid=26368943 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26368943 #FOAvip English Wikipedia <ref>{{Cite pmid|26368943 }}</ref> Basal forebrain neuronal inhibition enables rapid behavioral stopping #MMPMID26368943 Mayse JD ; Nelson GM ; Avila I ; Gallagher M ; Lin SC Nat Neurosci 2015[Oct]; 18 (10 ): 1501-8 PMID26368943 show ga Cognitive inhibitory control, the ability to rapidly suppress responses inappropriate for the context, is essential for flexible and adaptive behavior. Although most studies on inhibitory control have focused on the fronto-basal-ganglia circuit, we found that rapid behavioral stopping is enabled by neuronal inhibition in the basal forebrain (BF). In rats performing the stop signal task, putative noncholinergic BF neurons with phasic bursting responses to the go signal were nearly completely inhibited by the stop signal. The onset of BF neuronal inhibition was tightly coupled with and temporally preceded the latency to stop, the stop signal reaction time. Artificial inhibition of BF activity in the absence of the stop signal was sufficient to reproduce rapid behavioral stopping. These results reveal a previously unknown subcortical mechanism of rapid inhibitory control by the BF, which provides bidirectional control over the speed of response generation and inhibition. |*Inhibition, Psychological [MESH] |Animals [MESH] |Basal Forebrain/*physiology [MESH] |Behavior, Animal/*physiology [MESH] |Electrodes, Implanted [MESH] |Male [MESH] |Neural Inhibition/*physiology [MESH] |Rats [MESH] |Rats, Long-Evans [MESH]Basal forebrain neuronal inhibition enables rapid behavioral stopping (epmc).pdf DeepDyve Pubget Overpricing