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10.1111/1574-6976.12067 http://scihub22266oqcxt.onion/10.1111/1574-6976.12067 C7190074!7190074 !24499397     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24499397 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       FEMS+Microbiol+Rev 2014 ; 38 (5 ): 865-91 Nephropedia Template TP {{tp|p=24499397 |t=2014. Bacterial insertion sequences: their genomic impact and diversity |pdf=|usr=}}{{24499397 }} gab.com Text Bacterial insertion sequences: their genomic impact and diversity JO: FEMS Microbiol Rev http://www.kidney.de/pget.php?&tw=1&pmid=24499397 #FOAvip Insertion sequences (ISs), arguably the smallest and most numerous autonomous transposable elements (TEs), are important players in shaping their host genomes. This review focuses on prokaryotic ISs. We discuss IS distribution and impact on genome evolution. We also examine their effects on gene expression, especially their role in activating neighbouring genes, a phenomenon of particular importance in the recent upsurge of bacterial antibiotic resistance. We explain how ISs are identified and classified into families by a combination of characteristics including their transposases (Tpases), their overall genetic organisation and the accessory genes which some ISs carry. We then describe the organisation of autonomous and nonautonomous IS-related elements. This is used to illustrate the growing recognition that the boundaries between different types of mobile element are becoming increasingly difficult to define as more are being identified. We review the known Tpase types, their different catalytic activities used in cleaving and rejoining DNA strands during transposition, their organisation into functional domains and the role of this in regulation. Finally, we consider examples of prokaryotic IS domestication. In a more speculative section, we discuss the necessity of constructing more quantitative dynamic models to fully appreciate the continuing impact of TEs on prokaryotic populations. Twit Text FOAVip Bacterial insertion sequences: their genomic impact and diversity ????FEMS Microbiol Rev http://www.kidney.de/pget.php?&tw=1&pmid=24499397 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24499397 #FOAvip English Wikipedia <ref>{{Cite pmid|24499397 }}</ref> Bacterial insertion sequences: their genomic impact and diversity #MMPMID24499397 Siguier P ; Gourbeyre E ; Chandler M FEMS Microbiol Rev 2014[Sep]; 38 (5 ): 865-91 PMID24499397 show ga Insertion sequences (ISs), arguably the smallest and most numerous autonomous transposable elements (TEs), are important players in shaping their host genomes. This review focuses on prokaryotic ISs. We discuss IS distribution and impact on genome evolution. We also examine their effects on gene expression, especially their role in activating neighbouring genes, a phenomenon of particular importance in the recent upsurge of bacterial antibiotic resistance. We explain how ISs are identified and classified into families by a combination of characteristics including their transposases (Tpases), their overall genetic organisation and the accessory genes which some ISs carry. We then describe the organisation of autonomous and nonautonomous IS-related elements. This is used to illustrate the growing recognition that the boundaries between different types of mobile element are becoming increasingly difficult to define as more are being identified. We review the known Tpase types, their different catalytic activities used in cleaving and rejoining DNA strands during transposition, their organisation into functional domains and the role of this in regulation. Finally, we consider examples of prokaryotic IS domestication. In a more speculative section, we discuss the necessity of constructing more quantitative dynamic models to fully appreciate the continuing impact of TEs on prokaryotic populations. |*Genetic Variation [MESH] |*Genome, Bacterial [MESH] |Bacteria/enzymology/*genetics [MESH] |DNA Transposable Elements/*genetics [MESH] |Evolution, Molecular [MESH]Bacterial insertion sequences: their genomic impact and diversity (epmc).pdf DeepDyve Pubget Overpricing