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2014 ; 6
(11
): a016162
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Bacterial influences on animal origins
#MMPMID25280764
Alegado RA
; King N
Cold Spring Harb Perspect Biol
2014[Oct]; 6
(11
): a016162
PMID25280764
show ga
Animals evolved in seas teeming with bacteria, yet the influences of bacteria on
animal origins are poorly understood. Comparisons among modern animals and their
closest living relatives, the choanoflagellates, suggest that the first animals
used flagellated collar cells to capture bacterial prey. The cell biology of prey
capture, such as cell adhesion between predator and prey, involves mechanisms
that may have been co-opted to mediate intercellular interactions during the
evolution of animal multicellularity. Moreover, a history of bacterivory may have
influenced the evolution of animal genomes by driving the evolution of genetic
pathways for immunity and facilitating lateral gene transfer. Understanding the
interactions between bacteria and the progenitors of animals may help to explain
the myriad ways in which bacteria shape the biology of modern animals, including
ourselves.