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10.3389/fmicb.2015.00496

http://scihub22266oqcxt.onion/10.3389/fmicb.2015.00496
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suck abstract from ncbi

pmid26074894
      Front+Microbiol 2015 ; 6 (?): 496
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  • Bacterial exopolysaccharides: biosynthesis pathways and engineering strategies #MMPMID26074894
  • Schmid J ; Sieber V ; Rehm B
  • Front Microbiol 2015[]; 6 (?): 496 PMID26074894 show ga
  • Bacteria produce a wide range of exopolysaccharides which are synthesized via different biosynthesis pathways. The genes responsible for synthesis are often clustered within the genome of the respective production organism. A better understanding of the fundamental processes involved in exopolysaccharide biosynthesis and the regulation of these processes is critical toward genetic, metabolic and protein-engineering approaches to produce tailor-made polymers. These designer polymers will exhibit superior material properties targeting medical and industrial applications. Exploiting the natural design space for production of a variety of biopolymer will open up a range of new applications. Here, we summarize the key aspects of microbial exopolysaccharide biosynthesis and highlight the latest engineering approaches toward the production of tailor-made variants with the potential to be used as valuable renewable and high-performance products for medical and industrial applications.
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