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2018 ; 11
(ä): 103-112
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BOLD magnetic resonance imaging in nephrology
#MMPMID29559807
Hall ME
; Jordan JH
; Juncos LA
; Hundley WG
; Hall JE
Int J Nephrol Renovasc Dis
2018[]; 11
(ä): 103-112
PMID29559807
show ga
Magnetic resonance (MR) imaging, a non-invasive modality that provides anatomic
and physiologic information, is increasingly used for diagnosis of
pathophysiologic conditions and for understanding renal physiology in humans.
Although functional MR imaging methods were pioneered to investigate the brain,
they also offer powerful techniques for investigation of other organ systems such
as the kidneys. However, imaging the kidneys provides unique challenges due to
potential complications from contrast agents. Therefore, development of
non-contrast techniques to study kidney anatomy and physiology is important.
Blood oxygen level-dependent (BOLD) MR is a non-contrast imaging technique that
provides functional information related to renal tissue oxygenation in various
pathophysiologic conditions. Here we discuss technical considerations, clinical
uses and future directions for use of BOLD MR as well as complementary MR
techniques to better understand renal pathophysiology. Our intent is to summarize
kidney BOLD MR applications for the clinician rather than focusing on the complex
physical challenges that functional MR imaging encompasses; however, we briefly
discuss some of those issues.