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2014 ; 2014
(ä): 730814
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BLAT-based comparative analysis for transposable elements: BLATCAT
#MMPMID24959585
Lee S
; Oh S
; Kang K
; Han K
Biomed Res Int
2014[]; 2014
(ä): 730814
PMID24959585
show ga
The availability of several whole genome sequences makes comparative analyses
possible. In primate genomes, the priority of transposable elements (TEs) is
significantly increased because they account for ~45% of the primate genomes,
they can regulate the gene expression level, and they are associated with genomic
fluidity in their host genomes. Here, we developed the BLAST-like alignment tool
(BLAT) based comparative analysis for transposable elements (BLATCAT) program.
The BLATCAT program can compare specific regions of six representative primate
genome sequences (human, chimpanzee, gorilla, orangutan, gibbon, and rhesus
macaque) on the basis of BLAT and simultaneously carry out RepeatMasker and/or
Censor functions, which are widely used Windows-based web-server functions to
detect TEs. All results can be stored as a HTML file for manual inspection of a
specific locus. BLATCAT will be very convenient and efficient for comparative
analyses of TEs in various primate genomes.