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10.1016/j.healun.2016.01.1232 http://scihub22266oqcxt.onion/10.1016/j.healun.2016.01.1232 C4917469!4917469 !26996930     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26996930 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26996930 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Heart+Lung+Transplant 2016 ; 35 (6 ): 704-10 Nephropedia Template TP {{tp|p=26996930 |t=2016. B cells in transplantation |pdf=|usr=}}{{26996930 }} gab.com Text B cells in transplantation JO: J Heart Lung Transplant http://www.kidney.de/pget.php?&tw=1&pmid=26996930 #FOAvip B cell responses underlie the most vexing immunological barriers to organ transplantation. Much has been learned about the molecular mechanisms of B cell responses to antigen and new therapeutic agents that specifically target B cells or suppress their functions are available. Yet, despite recent advances, there remains an incomplete understanding about how B cell functions determine the fate of organ transplants and how, whether or when potent new therapeutics should optimally be used. This gap in understanding reflects in part the realization that besides producing antibodies, B cells can also regulate cellular immunity, contribute to the genesis of tolerance and induce accommodation. Whether non-specific depletion of B cells, their progeny or suppression of their functions would undermine these non-cognate functions and whether graft outcome would suffer as a result is unknown. These questions were discussed at a symposium on "B cells in transplantation" at the 2015 ISHLT annual meeting. Those discussions are summarized here and a new perspective is offered. Twit Text FOAVip B cells in transplantation ????J Heart Lung Transplant http://www.kidney.de/pget.php?&tw=1&pmid=26996930 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26996930 #FOAvip English Wikipedia <ref>{{Cite pmid|26996930 }}</ref> B cells in transplantation #MMPMID26996930 Dijke EI ; Platt JL ; Blair P ; Clatworthy MR ; Patel JK ; Kfoury AG ; Cascalho M J Heart Lung Transplant 2016[Jun]; 35 (6 ): 704-10 PMID26996930 show ga B cell responses underlie the most vexing immunological barriers to organ transplantation. Much has been learned about the molecular mechanisms of B cell responses to antigen and new therapeutic agents that specifically target B cells or suppress their functions are available. Yet, despite recent advances, there remains an incomplete understanding about how B cell functions determine the fate of organ transplants and how, whether or when potent new therapeutics should optimally be used. This gap in understanding reflects in part the realization that besides producing antibodies, B cells can also regulate cellular immunity, contribute to the genesis of tolerance and induce accommodation. Whether non-specific depletion of B cells, their progeny or suppression of their functions would undermine these non-cognate functions and whether graft outcome would suffer as a result is unknown. These questions were discussed at a symposium on "B cells in transplantation" at the 2015 ISHLT annual meeting. Those discussions are summarized here and a new perspective is offered. |*B-Lymphocytes [MESH] |Antibodies [MESH] |Graft Rejection [MESH] |Humans [MESH] |Immune Tolerance [MESH] |Immunity, Cellular [MESH]B cells in transplantation (epmc).pdf DeepDyve Pubget Overpricing