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10.15252/embj.201695134 http://scihub22266oqcxt.onion/10.15252/embj.201695134 C5007549!5007549 !27440401     free     free     free       EMBO+J 2016 ; 35 (17 ): 1845-7 Nephropedia Template TP {{tp|p=27440401 |t=2016. Autophagosome-lysosome fusion: PIs to the rescue |pdf=|usr=}}{{27440401 }} gab.com Text Autophagosome-lysosome fusion: PIs to the rescue JO: EMBO J http://www.kidney.de/pget.php?&tw=1&pmid=27440401 #FOAvip Phosphoinositides (PIs), a small fraction of the cellular lipids, function in almost all cellular physiological processes and especially in intracellular membrane trafficking events. PIs play a critical role in autophagy, but only PI(3)P is well studied. In this issue of The EMBO Journal, Hasegawa et al (2016) identified INPP5E, an inositol polyphosphate 5?phosphatase, as a novel regulator of autophagy. INPP5E controls the level of PI(3,5)P(2) at the lysosome and thereby locally regulates the actin cytoskeleton and autophagosome?lysosome fusion. Twit Text FOAVip Autophagosome-lysosome fusion: PIs to the rescue ????EMBO J http://www.kidney.de/pget.php?&tw=1&pmid=27440401 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27440401 #FOAvip English Wikipedia <ref>{{Cite pmid|27440401 }}</ref> Autophagosome-lysosome fusion: PIs to the rescue #MMPMID27440401 Li L ; Zhong Q EMBO J 2016[Sep]; 35 (17 ): 1845-7 PMID27440401 show ga Phosphoinositides (PIs), a small fraction of the cellular lipids, function in almost all cellular physiological processes and especially in intracellular membrane trafficking events. PIs play a critical role in autophagy, but only PI(3)P is well studied. In this issue of The EMBO Journal, Hasegawa et al (2016) identified INPP5E, an inositol polyphosphate 5?phosphatase, as a novel regulator of autophagy. INPP5E controls the level of PI(3,5)P(2) at the lysosome and thereby locally regulates the actin cytoskeleton and autophagosome?lysosome fusion. |*Autophagosomes [MESH] |*Lysosomes [MESH] |Autophagy [MESH] |Humans [MESH] |Membrane Fusion [MESH]Autophagosome-lysosome fusion: PIs to the rescue (epmc).pdf DeepDyve Pubget Overpricing