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10.4103/0972-2327.165454 http://scihub22266oqcxt.onion/10.4103/0972-2327.165454 C4683878!4683878 !26713011     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26713011 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Ann+Indian+Acad+Neurol 2015 ; 18 (4 ): 408-11 Nephropedia Template TP {{tp|p=26713011 |t=2015. Autoimmune encephalitis: Clinical diagnosis versus antibody confirmation |pdf=|usr=}}{{26713011 }} gab.com Text Autoimmune encephalitis: Clinical diagnosis versus antibody confirmation JO: Ann Indian Acad Neurol http://www.kidney.de/pget.php?&tw=1&pmid=26713011 #FOAvip CONTEXT: Autoimmune encephalitis is a heterogeneous disorder which is being diagnosed with increasing frequency. The diagnosis of these disorders is based on the detection of autoantibodies and characteristic clinical profiles. AIMS: We aimed to study the antibody profile in encephalitis patients with suspected autoimmune etiology presenting to a tertiary care center. SETTINGS AND DESIGN: The subjects were selected by screening all patients with clinical profile suggesting autoimmune encephalitis admitted in the neuromedical intensive care unit (ICU) of a tertiary care center in South India. MATERIALS AND METHODS: Patients who fulfilled modified Zuliani et al.'s, criteria for autoimmune encephalitis were identified during the period December 2009-June 2013. Blood samples from these subjects were screened for six neuronal antibodies. STATISTICAL ANALYSIS USED: Chi-square test was applied to compare the antibody positive and negative patients. RESULTS: Out of 1,227 patients screened, 39 subjects (14 males: 25 females) were identified with a mean age of 15.95 years and 19 cases were assessed in the acute and 20 in the convalescent phase of the illness. Seizure (87.8 %) was the most common presenting symptom; status epilepticus occurred in 23 (60.5%) patients during the course of the illness. Fourteen (35.9%) patients were N-methyl-D-aspartate receptor (NMDAR) antibody-positive and all were negative for the other antibodies tested. CONCLUSIONS: One-third of patients presenting with acute noninfective encephalitis would be positive for NMDAR antibodies with the remaining two-thirds with clinically suspected autoimmune encephalitis being antibody-negative. There are few markers in the clinical and investigative profiles to distinguish antibody-positive and -negative patients. Twit Text FOAVip Autoimmune encephalitis: Clinical diagnosis versus antibody confirmation ????Ann Indian Acad Neurol http://www.kidney.de/pget.php?&tw=1&pmid=26713011 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26713011 #FOAvip English Wikipedia <ref>{{Cite pmid|26713011 }}</ref> Autoimmune encephalitis: Clinical diagnosis versus antibody confirmation #MMPMID26713011 Cyril AC ; Nair SS ; Mathai A ; Kannoth S ; Thomas SV Ann Indian Acad Neurol 2015[Oct]; 18 (4 ): 408-11 PMID26713011 show ga CONTEXT: Autoimmune encephalitis is a heterogeneous disorder which is being diagnosed with increasing frequency. The diagnosis of these disorders is based on the detection of autoantibodies and characteristic clinical profiles. AIMS: We aimed to study the antibody profile in encephalitis patients with suspected autoimmune etiology presenting to a tertiary care center. SETTINGS AND DESIGN: The subjects were selected by screening all patients with clinical profile suggesting autoimmune encephalitis admitted in the neuromedical intensive care unit (ICU) of a tertiary care center in South India. MATERIALS AND METHODS: Patients who fulfilled modified Zuliani et al.'s, criteria for autoimmune encephalitis were identified during the period December 2009-June 2013. Blood samples from these subjects were screened for six neuronal antibodies. STATISTICAL ANALYSIS USED: Chi-square test was applied to compare the antibody positive and negative patients. RESULTS: Out of 1,227 patients screened, 39 subjects (14 males: 25 females) were identified with a mean age of 15.95 years and 19 cases were assessed in the acute and 20 in the convalescent phase of the illness. Seizure (87.8 %) was the most common presenting symptom; status epilepticus occurred in 23 (60.5%) patients during the course of the illness. Fourteen (35.9%) patients were N-methyl-D-aspartate receptor (NMDAR) antibody-positive and all were negative for the other antibodies tested. CONCLUSIONS: One-third of patients presenting with acute noninfective encephalitis would be positive for NMDAR antibodies with the remaining two-thirds with clinically suspected autoimmune encephalitis being antibody-negative. There are few markers in the clinical and investigative profiles to distinguish antibody-positive and -negative patients. äAutoimmune encephalitis: Clinical diagnosis versus antibody confirmati(epmc).pdf DeepDyve Pubget Overpricing