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Continuum (Minneap Minn)
2016[Dec]; 22
(6, Muscle and Neuromuscular Junction Disorders
): 1852-1870
PMID27922497
show ga
PURPOSE OF REVIEW: This article provides guidelines for diagnosing and treating
the different subtypes of autoimmune myopathies. RECENT FINDINGS: The most common
subtypes of autoimmune myopathies are dermatomyositis, immune-mediated
necrotizing myopathy, antisynthetase syndrome, and overlap syndromes; isolated
polymyositis is an exceptionally rare disease. Specific autoantibodies are
associated with unique clinical phenotypes and may be used for diagnostic and
prognostic purposes, such as to assess the risk of coexisting malignancy.
SUMMARY: Diagnosing the specific subtype of autoimmune myopathy can be achieved
by combining relevant features of the history, neuromuscular examination, muscle
biopsy, and serologic studies.