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10.1101/cshperspect.a020628 http://scihub22266oqcxt.onion/10.1101/cshperspect.a020628 C4448607!4448607 !25877220     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25877220 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25877220 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Cold+Spring+Harb+Perspect+Biol 2015 ; 7 (6 ): ä Nephropedia Template TP {{tp|p=25877220 |t=2015. Astrocytes in neurodegenerative disease |pdf=|usr=}}{{25877220 }} gab.com Text Astrocytes in neurodegenerative disease JO: Cold Spring Harb Perspect Biol http://www.kidney.de/pget.php?&tw=1&pmid=25877220 #FOAvip Astrocytes contribute to the maintenance of the health and function of the central nervous system (CNS). Thus, it is not surprising that these multifunctional cells have been implicated in the onset and progression of several neurodegenerative diseases. The involvement of astrocytes in the neuropathology of these diseases is likely a consequence of both the loss of normal homeostatic functions and gain of toxic functions. Intracellular aggregates in astrocytes are a common feature of various neurodegenerative diseases, and these aggregates perturb normal astrocytic functions in ways that can be harmful to neuronal viability. Here, we review the role of astrocytes in neurodegenerative diseases, focusing on their dysfunction in Huntington's disease (HD), Parkinson's disease (PD), Alzheimer's disease (AD), and amyotrophic lateral sclerosis (ALS). Twit Text FOAVip Astrocytes in neurodegenerative disease ????Cold Spring Harb Perspect Biol http://www.kidney.de/pget.php?&tw=1&pmid=25877220 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25877220 #FOAvip English Wikipedia <ref>{{Cite pmid|25877220 }}</ref> Astrocytes in neurodegenerative disease #MMPMID25877220 Phatnani H ; Maniatis T Cold Spring Harb Perspect Biol 2015[Apr]; 7 (6 ): ä PMID25877220 show ga Astrocytes contribute to the maintenance of the health and function of the central nervous system (CNS). Thus, it is not surprising that these multifunctional cells have been implicated in the onset and progression of several neurodegenerative diseases. The involvement of astrocytes in the neuropathology of these diseases is likely a consequence of both the loss of normal homeostatic functions and gain of toxic functions. Intracellular aggregates in astrocytes are a common feature of various neurodegenerative diseases, and these aggregates perturb normal astrocytic functions in ways that can be harmful to neuronal viability. Here, we review the role of astrocytes in neurodegenerative diseases, focusing on their dysfunction in Huntington's disease (HD), Parkinson's disease (PD), Alzheimer's disease (AD), and amyotrophic lateral sclerosis (ALS). |Animals [MESH] |Astrocytes/*physiology [MESH] |Dementia/*physiopathology [MESH] |Humans [MESH] |Neurodegenerative Diseases/*physiopathology [MESH]Astrocytes in neurodegenerative disease (epmc).pdf DeepDyve Pubget Overpricing