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10.1016/j.conb.2017.02.008 http://scihub22266oqcxt.onion/10.1016/j.conb.2017.02.008 C5511068!5511068!28284099     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28284099.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Curr+Opin+Neurobiol 2017 ; 44 (ä): 28-33 Nephropedia Template TP {{tp|p=28284099|t=2017. Astrocytes and the Modulation of Sleep |pdf=|usr=}}{{28284099}} gab.com Text Astrocytes and the Modulation of Sleep JO: Curr Opin Neurobiol http://www.kidney.de/pget.php?&tw=1&pmid=28284099 #FOAvip Astrocytes are being identified as having multiple roles in sleep. Initially they were shown to modulate the process of sleep homeostasis through the release of adenosine which acts on adenosine A1 receptors (A1R) to promote sleep drive. More recent studies indicate that the astrocyte also plays pivotal, sleep-dependent roles in ?cleaning the brain? during sleep. This work indicates that a glymphatic pathway that critically relies on astrocytic aquaporin 4, is able to flush solutes from the brain and that deficits in this pathway may contribute to Alzheimer?s disease. Finally, astrocytes are known to play important metabolic roles and provide energy on demand to neurons through an astrocyte-neuron shuttle. Given that the time course of astrocytic function is orders of magnitude slower than that of the neuron, this non-neuronal cell is perfectly tuned to modulating slow, state dependent changes in the brain. Twit Text FOAVip Astrocytes and the Modulation of Sleep ????Curr Opin Neurobiol http://www.kidney.de/pget.php?&tw=1&pmid=28284099 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28284099 #FOAvip English Wikipedia <ref>{{Cite pmid|28284099}}</ref> Astrocytes and the Modulation of Sleep #MMPMID28284099 Haydon PG Curr Opin Neurobiol 2017[Jun]; 44 (ä): 28-33 PMID28284099show ga Astrocytes are being identified as having multiple roles in sleep. Initially they were shown to modulate the process of sleep homeostasis through the release of adenosine which acts on adenosine A1 receptors (A1R) to promote sleep drive. More recent studies indicate that the astrocyte also plays pivotal, sleep-dependent roles in ?cleaning the brain? during sleep. This work indicates that a glymphatic pathway that critically relies on astrocytic aquaporin 4, is able to flush solutes from the brain and that deficits in this pathway may contribute to Alzheimer?s disease. Finally, astrocytes are known to play important metabolic roles and provide energy on demand to neurons through an astrocyte-neuron shuttle. Given that the time course of astrocytic function is orders of magnitude slower than that of the neuron, this non-neuronal cell is perfectly tuned to modulating slow, state dependent changes in the brain. äAstrocytes and the Modulation of Sleep (epmc).pdf DeepDyve Pubget Overpricing