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10.1038/srep32599

http://scihub22266oqcxt.onion/10.1038/srep32599
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C5009334!5009334 !27586642
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suck abstract from ncbi


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pmid27586642
      Sci+Rep 2016 ; 6 (ä): 32599
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  • Arterial stiffness &Sri Lankan chronic kidney disease of unknown origin #MMPMID27586642
  • Gifford F ; Kimmitt R ; Herath C ; Webb DJ ; Melville V ; Siribaddana S ; Eddleston M ; Dhaun N
  • Sci Rep 2016[Sep]; 6 (ä): 32599 PMID27586642 show ga
  • Chronic kidney disease (CKD) is common and independently associated with cardiovascular disease (CVD). Arterial stiffness contributes to CVD risk in CKD. In many developing countries a considerable proportion of CKD remains unexplained, termed CKDu. We assessed arterial stiffness in subjects with Sri Lankan CKDu, in matched controls without CKD and in those with defined CKD. Aortic blood pressure (BP), pulse wave velocity (PWV) and augmentation index (AIx) were assessed in 130 subjects (50 with CKDu, 45 with CKD and 35 without CKD) using the validated TensioMed? Arteriograph monitor. Brachial and aortic BP was lower in controls than in CKDu and CKD subjects but no different between CKDu and CKD. Controls had a lower PWV compared to subjects with CKDu and CKD. Despite equivalent BP and renal dysfunction, CKDu subjects had a lower PWV than those with CKD (8.7?±?1.5?vs. 9.9?±?2.2?m/s, p?
  • |Blood Pressure/physiology [MESH]
  • |Diabetes Mellitus/physiopathology [MESH]
  • |Female [MESH]
  • |Humans [MESH]
  • |Kidney Failure, Chronic/*physiopathology [MESH]
  • |Male [MESH]
  • |Middle Aged [MESH]
  • |Pulse Wave Analysis [MESH]
  • |Sri Lanka [MESH]
  • |Systole/physiology [MESH]


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