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10.1038/nrn.2015.2

http://scihub22266oqcxt.onion/10.1038/nrn.2015.2
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C4899966!4899966 !26656253
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suck abstract from ncbi


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pmid26656253
      Nat+Rev+Neurosci 2016 ; 17 (1 ): 36-44
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  • Applications of CRISPR-Cas systems in neuroscience #MMPMID26656253
  • Heidenreich M ; Zhang F
  • Nat Rev Neurosci 2016[Jan]; 17 (1 ): 36-44 PMID26656253 show ga
  • Genome-editing tools, and in particular those based on CRISPR-Cas (clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR-associated protein) systems, are accelerating the pace of biological research and enabling targeted genetic interrogation in almost any organism and cell type. These tools have opened the door to the development of new model systems for studying the complexity of the nervous system, including animal models and stem cell-derived in vitro models. Precise and efficient gene editing using CRISPR-Cas systems has the potential to advance both basic and translational neuroscience research.
  • |*Genetic Engineering [MESH]
  • |*Neurosciences [MESH]
  • |*Translational Research, Biomedical [MESH]
  • |Animals [MESH]
  • |CRISPR-Cas Systems/*physiology [MESH]
  • |Clustered Regularly Interspaced Short Palindromic Repeats/*physiology [MESH]


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