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10.1155/2014/764581

http://scihub22266oqcxt.onion/10.1155/2014/764581
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C4026877!4026877 !24895607
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suck abstract from ncbi


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pmid24895607
      Biomed+Res+Int 2014 ; 2014 (ä): 764581
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  • Application of proteomics and peptidomics to COPD #MMPMID24895607
  • Pelaia G ; Terracciano R ; Vatrella A ; Gallelli L ; Busceti MT ; Calabrese C ; Stellato C ; Savino R ; Maselli R
  • Biomed Res Int 2014[]; 2014 (ä): 764581 PMID24895607 show ga
  • Chronic obstructive pulmonary disease (COPD) is a complex disorder involving both airways and lung parenchyma, usually associated with progressive and poorly reversible airflow limitation. In order to better characterize the phenotypic heterogeneity and the prognosis of patients with COPD, there is currently an urgent need for discovery and validation of reliable disease biomarkers. Within this context, proteomic and peptidomic techniques are emerging as very valuable tools that can be applied to both systemic and pulmonary samples, including peripheral blood, induced sputum, exhaled breath condensate, bronchoalveolar lavage fluid, and lung tissues. Identification of COPD biomarkers by means of proteomic and peptidomic approaches can thus also lead to discovery of new molecular targets potentially useful to improve and personalize the therapeutic management of this widespread respiratory disease.
  • |Bronchoalveolar Lavage [MESH]
  • |Humans [MESH]
  • |Peptides/*metabolism [MESH]
  • |Proteomics/*methods [MESH]
  • |Pulmonary Disease, Chronic Obstructive/blood/*metabolism/therapy [MESH]
  • |Respiration [MESH]


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