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10.2174/1570159x14666160606093602 http://scihub22266oqcxt.onion/10.2174/1570159x14666160606093602 C5327459!5327459 !27264948     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27264948 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Curr+Neuropharmacol 2017 ; 15 (1 ): 174-183 Nephropedia Template TP {{tp|p=27264948 |t=2017. Antipsychotic Induced Dopamine Supersensitivity Psychosis: A Comprehensive Review |pdf=|usr=}}{{27264948 }} gab.com Text Antipsychotic Induced Dopamine Supersensitivity Psychosis: A Comprehensive Review JO: Curr Neuropharmacol http://www.kidney.de/pget.php?&tw=1&pmid=27264948 #FOAvip Chronic prescription of antipsychotics seems to lose its therapeutic benefits in the prevention of recurring psychotic symptoms. In many instances, the occurrence of relapse from initial remission is followed by an increase in dose of the prescribed antipsychotic. The current understanding of why this occurs is still in its infancy, but a controversial idea that has regained attention recently is the notion of iatrogenic dopamine supersensitivity. Studies on cell cultures and animal models have shown that long-term antipsychotic use is linked to both an upregulation of dopamine D<sub>2</sub>-receptors in the striatum and the emergence of enhanced receptor affinity to endogenous dopamine. These findings have been hypothesized to contribute to the phenomenon known as dopamine supersensitivity psychosis (DSP), which has been clinically typified as the foundation of rebound psychosis, drug tolerance, and tardive dyskinesia. The focus of this review is the update of evidence behind the classification of antipsychotic induced DSP and an investigation of its relationship to treatment resistance. Since antipsychotics are the foundation of illness management, a greater understanding of DSP and its prevention may greatly affect patient outcomes. Twit Text FOAVip Antipsychotic Induced Dopamine Supersensitivity Psychosis: A Comprehensive Review ????Curr Neuropharmacol http://www.kidney.de/pget.php?&tw=1&pmid=27264948 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27264948 #FOAvip English Wikipedia <ref>{{Cite pmid|27264948 }}</ref> Antipsychotic Induced Dopamine Supersensitivity Psychosis: A Comprehensive Review #MMPMID27264948 Yin J ; Barr AM ; Ramos-Miguel A ; Procyshyn RM Curr Neuropharmacol 2017[]; 15 (1 ): 174-183 PMID27264948 show ga Chronic prescription of antipsychotics seems to lose its therapeutic benefits in the prevention of recurring psychotic symptoms. In many instances, the occurrence of relapse from initial remission is followed by an increase in dose of the prescribed antipsychotic. The current understanding of why this occurs is still in its infancy, but a controversial idea that has regained attention recently is the notion of iatrogenic dopamine supersensitivity. Studies on cell cultures and animal models have shown that long-term antipsychotic use is linked to both an upregulation of dopamine D<sub>2</sub>-receptors in the striatum and the emergence of enhanced receptor affinity to endogenous dopamine. These findings have been hypothesized to contribute to the phenomenon known as dopamine supersensitivity psychosis (DSP), which has been clinically typified as the foundation of rebound psychosis, drug tolerance, and tardive dyskinesia. The focus of this review is the update of evidence behind the classification of antipsychotic induced DSP and an investigation of its relationship to treatment resistance. Since antipsychotics are the foundation of illness management, a greater understanding of DSP and its prevention may greatly affect patient outcomes. |Animals [MESH] |Antipsychotic Agents/*adverse effects [MESH] |Dopamine Agents/*therapeutic use [MESH] |Gene Expression Regulation/drug effects [MESH] |Humans [MESH] |Psychotic Disorders/*drug therapy/*etiology [MESH]Antipsychotic Induced Dopamine Supersensitivity Psychosis: A Comprehen(epmc).pdf DeepDyve Pubget Overpricing