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10.1007/s00280-015-2903-8 http://scihub22266oqcxt.onion/10.1007/s00280-015-2903-8 C4648954!4648954 !26563258     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26563258 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26563258 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Cancer+Chemother+Pharmacol 2015 ; 76 (6 ): 1101-12 Nephropedia Template TP {{tp|p=26563258 |t=2015. Antimitotic drugs in the treatment of cancer |pdf=|usr=}}{{26563258 }} gab.com Text Antimitotic drugs in the treatment of cancer JO: Cancer Chemother Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=26563258 #FOAvip Cancer is a complex disease since it is adaptive in such a way that it can promote proliferation and invasion by means of an overactive cell cycle and in turn cellular division which is targeted by antimitotic drugs that are highly validated chemotherapy agents. However, antimitotic drug cytotoxicity to non-tumorigenic cells and multiple cancer resistance developed in response to drugs such as taxanes and vinca alkaloids are obstacles faced in both the clinical and basic research field to date. In this review, the classes of antimitotic compounds, their mechanisms of action and cancer cell resistance to chemotherapy and other limitations of current antimitotic compounds are highlighted, as well as the potential of novel 17-? estradiol analogs as cancer treatment. Twit Text FOAVip Antimitotic drugs in the treatment of cancer ????Cancer Chemother Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=26563258 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26563258 #FOAvip English Wikipedia <ref>{{Cite pmid|26563258 }}</ref> Antimitotic drugs in the treatment of cancer #MMPMID26563258 van Vuuren RJ ; Visagie MH ; Theron AE ; Joubert AM Cancer Chemother Pharmacol 2015[Dec]; 76 (6 ): 1101-12 PMID26563258 show ga Cancer is a complex disease since it is adaptive in such a way that it can promote proliferation and invasion by means of an overactive cell cycle and in turn cellular division which is targeted by antimitotic drugs that are highly validated chemotherapy agents. However, antimitotic drug cytotoxicity to non-tumorigenic cells and multiple cancer resistance developed in response to drugs such as taxanes and vinca alkaloids are obstacles faced in both the clinical and basic research field to date. In this review, the classes of antimitotic compounds, their mechanisms of action and cancer cell resistance to chemotherapy and other limitations of current antimitotic compounds are highlighted, as well as the potential of novel 17-? estradiol analogs as cancer treatment. |Antimitotic Agents/classification/*therapeutic use [MESH] |Apoptosis/*drug effects [MESH] |Biomarkers, Tumor/metabolism [MESH] |Cell Cycle/*drug effects [MESH] |Cell Proliferation/*drug effects [MESH] |Drug Resistance, Neoplasm [MESH] |Humans [MESH] |Neoplasms/*drug therapy/metabolism [MESH] |Taxoids/therapeutic use [MESH]Antimitotic drugs in the treatment of cancer (epmc).pdf DeepDyve Pubget Overpricing